Nobel Prize in Chemistry was awarded to Eric Betzig, Stefan W. Hell and William E. Moerner for fluorescence microscopy studies. Scientists awarded for the solution of a problem, but by two different methods: Hell has
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Nobel Prize in Chemistry was awarded to Eric
Betzig, Stefan W. Hell and William E. Moerner for
fluorescence microscopy studies.
Scientists awarded for the solution of a problem, but by two different methods: Hell has developed the so-called STED-microscopy and Betzig and Moerner - single-molecule microscopy.
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Method of fluorescence microscopy - painting objects with
special non-toxic substances capable of light when irradiated with
ultraviolet rays.
This method gave better resolution than visual.
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Eric Betzig
Born: 1960, Ann Arbor, USA
Affiliation at the
time of the award:
Janelia Research Campus, Howard Hughes
Medical Institute, Ashburn,USA
Prize motivation: "for the development of super-resolved fluorescence microscopy"
Field: physical chemistry
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Stefan W. Hell
Born: 1962, Arad, Romania
Affiliation at
the time of the award:
Max Planck Institute for
Biophysical Chemistry, German Cancer Research Center
Prize motivation: "for the development of super-resolved fluorescence microscopy
"Field: physical chemistry
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William E. Moerner
Born: 1953
Affiliation at the time of
the award:
Stanford University, Stanford, CA, USA
Prize motivation: "for
the development of super-resolved fluorescence microscopy"
Field: physical chemistry
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(Вид микротрубок в оптический микроскоп и с помощью
флоурeсцентной микроскопии.)
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Scientists invented and synthesized various molecules that are
"attached" to the protein and when exposed to ultraviolet
radiation emit visible light.
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Specific molecule is attached to a specific protein
in certain quantities, so that scientists can trace which
molecule is involved in various processes.
Active and inactive proteins have slightly different formulas that scientists can observe the activation of proteins.
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Mouse after the action method of fluorescence microscopy
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Scientists with fluorescence microscopy technique and technical innovations
were able to overcome the inviolable laws of nature
and use it in medicine and science.
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In his presentation, we used material from these