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Evolution of surgery
Introduction to modern surgery
Short history of
the Medical School of Debrecen and the Surgical Institute
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„The abdomen, the chest and the brain will
forever be shut from the intrusion of the wise
and humane surgeon.”
Sir John Ericksen, Surgeon Extraordinaire to Queen Victoria, 1837
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„Today our colleagues perform an average of 80.000
operations each day (in the USA), many in the
abdomen, chest or brain”
Daniel J. Riskin, UCLA, 2006
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Epochs of Surgery
Characteristics of the pre-modern phase:
Lack of
significant anatomical knowledge
Progress was made by the isolated achievement
of outstanding personalities
Methods were tested during major wars under the pressure of necessity
Clerical dogmas prevailed over scientific contributions
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Medical heritage of early civilizations
The earliest written piece
of medical history, 1600-1500 B.C. Edwin Smith Egyptian papyrus:
surgery
was well defined, having important role in medicine
contains case reports in a logically arranged series
personal cleanliness, hygiene and correct diagnosis before treatment was important
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Scope of surgical activities
Bandages, dressings
Circumcision
Opening abscesses
Fractures, dislocations
Lithotomies (urolith)
Hemorrhoides,
fistulas
Amputations
Tooth extractions
Herniotomies
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Hippocrates (460-375 b.c.)
„The father of medicine”
Medicine and surgery
was one discipline
Great attention to observation, detail, record keeping,
gathering knowledge about diseases, cleanliness, order, practice
„Humoralpathology”
Corpus Hippocraticum, devotion to the patient,
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Ancient textbooks
Ayur Veda (The book of life) India,
China
Code of Hammurabi 2000 B.C. Mesopotamia) (Surg., Medical, Legal
text)
Alexandria: Aristotle, Herophilos, Erasistratos
Roman empire: Celsus 8 books, Galenus (treated gladiators, dissected pigs, many errors, great impact until XV. century, disagreement was heresy)
Arabic period, Avicenna (Persian) Xth century:
The Canon (surgery as a necessary evil, Baghdad, Damascus, Cairo: hospital-med. schools)
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Medieval medicine (476-1453)
Religious medicine, dogmas
Low social status of
surgeons
Surgery practiced by barber surgeons
Clerical ban on autopsies, absense
of anatomical knowledge (dissection on pigs)
Miracles made by saints
Illnes is a retribution from heaven
Hospitals maintained by the church
The sick taken care of by nuns
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The Salerno School
First school of formal training,commenced in
the 12th century, southern Italy
The first secular medical school
Revival
of ancient knowledge
Dissection on pigs
More emphasis on surgery
Recording own experience of surgeons
Roger of Salerno: Cyrurgia Rigerii 1170- the first independent surgical work in the West
The school moves to Bologna after his death
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Development of medicine in the middle ages
Lanfranc 1315.
France, against „pus bonum et laudabile” keep it clean
Pope
Sixtus IV. (1414-1484) appr. autopsies, stimulation of studies
Leonardo da Vinci, Michelangelo, Dürer, Titian…
Jacob Sylvius, Paris: Galen’s anatomy
Andreas Vesalius, Brussels: at age 23, professor of surgery
De Humani Corporis fabrica (at age 28)
Paracelsus, Basel:
„internal medicine and surgery must not be separated”
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Ambroise Paré 1510-1590
Apprentice of Vesalius
Field surgeon in the
French army
Performed autopsies
Used turpentine, instead of burning oil to
treat gunshot wounds, amputated limbs
Routine ligature of vessels
Invented new instruments, limb prostheses
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XVIII. Enlightenment
Revival of ancient medical knowledge
William and John
Hunter
Anatomy of the gravid uterus (William)
Ligature of the
aneurysm of the superficial fem. art. (instead of amputation) in four cases succesfully
Angina pectoris in his own case (John)
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Beginning of modern surgery
Phase I:
introduction of
anaesthesia (Morton)
anesthetic – the agent
1842. January: William E. Clarke
tooth extraction under ether narcosis Rochester, NY
1846. October: Dr.John C. Warren (NEJM, AMA, 1st dean of Harvard) jaw tumor removal under ether narcosis performed by William T.G. Morton
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Early development of biomedical sciences
Edward Jenner (surgeon): 1749-1823
Vaccination, pox
Theodor Schwann:
1810-1882, cells
Rudolf Virchow
1821-1902, cellular
pathology
Francois Magendie
1783-1855, nervous system anatomy
Claude Bernard
1813-1878, experimental physiology homeostasis
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Antisepsis-asepsis, II. phase
Louis Pasteur: correlation between rotting and
oxygen content of the air, discovery of bacteria
Joseph Lister:
carbolic acid used for sanitation in Carlisle, wound toilette, and operating instruments, death rate dropped to 1/3, lead and zinc plates to cover wounds
Semmelweis Ignácz: hypochloric acid for decontamination of the hand after autopsies
R.Koch: TB, anthrax, steem for sterilization
Trendelenburg, Schimmelbusch: steam sterilization
Steril rubber gloves: Halsted 1891.
Face mask: Hunter 1900.
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The first (surgical)
Nobel Prize in medicine
Theodor Kocher
1841-1917. Bern
1909:
„…for his work in physiology, pathology and surgery
on the thyroid gland…”
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Features of modern surgery
High degree of specialization (heart,
vascular, chest, pediatric, colorectal…)
Maximum use of related sciences (rtg,
US, CT, MRI, laboratory tests, endoscopy…)
Fast and wide share of information
Research oriented development of surgery guided by the rules of science and law
and grants!
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Independent disciplines sprouting from general surgery
Urology
Orthopedics
Radiology
Traumatology
Chest surgery
Heart surgery
Pediatric
surgery
Hand surgery
Vascular s.
Transplantation s.
Neurosurgery
Head and neck s.
Ophtalmic s.
Plastic s.
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Cooperation between disciplines
„Clinical Sciences”
Anesthesiology, ICU
Imaging: US, CT, MR,
PET, nuclear medicine
Laboratory diagnostics, microbiology lab
Internal medicine (gastroent., endocrin.,
cardiol., nephrol…)
Surgery
Theoretical Sciences”
Anatomy, physiol., chemistry, physics
Pharmacology
Engineering (sterilization, lighting, laparoscopy, endoscopy, US cutting devices, staplers, implants
Immunology (transfusion, transplantation…)
Genetics (FAP, HNPCC…)
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Historical moments of the University of Debrecen
Calvinist Coll.
1541
University XVII th century
1750- István Hatvani: natural sciences in
the curricula
1906. Gyula Kenézy, theol., law, science and medical faculties
1914-1918. University of Arts and Sciences, Floris Korb
1921: Inauguration of the Medical Faculty
Four out of 15 professors stay in Debrecen during WW II
1951: Med. Fac. becomes and independent university: DOTE
1977: Dentistry Fac. founded
1987: English Program initiated
1998: University Assoc. of Debrecen DATE, DOTE, KLTE, KFRTF, LFZFDK, ATOMKI, DRHE
2000: UD MHSC