Презентация на тему Jsc “astana medical university”

airway obstruction in the recently extubated intensive care unit

(ICU) patient. Depending upon the severity of edema, patients may go on to develop “a high pitched noisy respiration” known as “stridor”
(1). Stridor has been documented to occur in 3.5-36.8% of the ICU population, depending on the definition used
(2). Stridor not only leads to anxiety for the patient and family, but may progress to acute respiratory failure requiring reintubation and resulting in increased mechanical ventilation days, ICU days, patient care costs, morbidity, and mortality.

syphylisnof larynx
Infections in neighbourhood
peritonsillar abscess, retropharyngeal abscess,

ludwings angina
Trauma
surgery of tongue, laryngeal trauma, endoscopy, inhalation, irritant gases, thermal, chemical burns, intubation
Neoplasm Cancer of larynx or laryngopharynx often assoc iated with deep ulceration
Allergy
angioneurotic edema, anaphylaxis
Radiation: For cancer of larynx or pharynx.
Systemic disease : Nephritis, heart failure, or myxoedema.

Etiology

supraglottic or subglottic region. Children may require direct laryngoscopy.
Symptoms and signs

every 15 minutes
Steroids are useful in epiglottitis, laryngo- tracheo-bronchitis or

oedema due to traumatic allergic or post-radiation causes.

Management

need for reintubation in patients at increased risk for

extubation failure due to airway edema. Steroid therapy should be administered >6 hours prior to extubation to be effective in reducing airway edema.
Level 2: Patients at risk for laryngeal edema include: Traumatic intubation Female gender Prolonged intubation (>7 days) Traumatic injury Oversized endotracheal tubes Self extubation Failed cuff leak test The cuff leak test is an adequate test to assess for laryngeal edema.
Level 3: A leak of greater than 30% of the administered tidal volume upon deflation of the endotracheal tube cuff is suggestive of successful extubation. When steroids are administered to decrease post-extubation stridor, dexamethasone 4 mg IV q 6 hrs should be utilized.

Managenment

of the airway that may affect the supraglottis, glottis,

and/or subglottis. It can be defined as a partial or circumferential narrowing of the endolaryngeal airway and may be congenital or acquired. The subglottis is the most common site of involvement.

Laryngeal stenosis

post surgery
post radiotherapy
thermal/ chemical burns

histoplasmosis
diphtheria
syphilis

3. Benign disorders
intrinsic
papilloma/chondroma
minor salivary

gland / nerve sheath tumor
extrinsic
Thyroid/ thymic tumors

tumor
sarcoma/ lymphomas
Extrinsic
Thyroid malignancy
5. Collagen vascular

disorders
Wegeners granulomatosis
Relapsing poly chondritis

gives idea regarding time/ frequency of intervention, surgical procedure

required and its outcome.
Endotracheal intubartion
ischemic necrosis ( pressure )
mucosal ulcer+ inflammation = fibrosis
others: duration, composition/ size of tube, laryngeal movement.
primary site ; post glottis.

mucosal disruption
hematoma:
cartilage loss
heals by fibrosis
secondary

infection
OTHERS:
DM, CCF, stroke, GERD.
idiopathic- females (estrogen- TGFβ ).

process adhesion
TYPE 2 post commissure stenosis with
interarytenoid plane

scarring.
TYPE 3 post commissure stenosis with
ankylosis of unilat crico arytenoid joint
TYPE 4 post commissure stenosis with bilateral
cricoarytenoid joint ankylosis.

1-subglottic / tracheal stenosis

subglottic stenosis <1 cm within
cricoid ring without glottic / tracheal
extension.
GRADE 3-subglottic leison with extn upto upper
trachea but no glottic involvement.
GRADE 4-glottic involvement with fixation/
paralysis of one/ both vocal folds.

obstruction. Supraglottic or glottic obstruction generally presents as inspiratory

stridor, while narrowing between the glottis through the trachea is associated with biphasic stridor.
Other symptoms include episodes of apnea, suprasternal and subcostal retractions, tachypnea, and dyspnea. Hypoxia can result in cyanosis and anxiety. If the glottis is involved, symptoms of hoarseness or weak husky cry, aphonia, or dysphagia may be noted.

Manifestation

airway, voice, and feeding. Progressive respiratory difficulty is the

prime symptom of airway obstruction with biphasic stridor, dyspnea, air hunger, and vigorous efforts of breathing with suprasternal, intercostal, and diaphragmatic retraction. Abnormal cry, aphonia, or hoarseness occurs when the vocal cords are affected. Dysphagia and feeding abnormality with recurrent aspiration and pneumonia can occur.

onset, effect on airway, voice etc…
Indirect/ Direct laryngoscopy,

Bronchoscopy, PFT
HRCT with 3-D reconstruction, virtual endoscopy
Timing of repair: granlomatous/autoimmune disorders require stabilisation of underlying disease process .

of the airway. Radiography helps assess the exact site

and length of the stenotic segment, especially for totally obliterated airways.
Endoscopy Indirect laryngoscopy alone is inadequate for diagnosis. Direct endoscopic visualization of the larynx is essential to study the stenosis carefully. Flexible fiberoptic endoscopy assesses the dynamics of vocal cord function and the upper airway, including the trachea (Vauthy and Reddy, 1980). In patients with severe burns with neck contractures, flexible endoscopy may be the only method to visualize the larynx. Flexible retrograde tracheoscopy through the tracheostomy site may add some useful information in some cases.
Psychoacoustic evaluation and acoustic analysis of the voice may be used to establish the degree of vocal abnormality before surgery and compare it after surgery (Dedo and Rowe, 1983; Zalzal et al, 1991). Videostrobolaryngoscopy helps in assessment of vocal cord function in adults. 12 Pulmonary function tests with either the spirometric maximum inspiration and expiration flow rates, flow volume loops, or pressure flow loops show characteristic changes in upper airway stenosis and can be used to compare the postoperative results with preoperative values (Brookes and Fairfax, 1982; Grahne et al, 1983; Hallenborh et al, 1982; Zalzal et al, 1990).

Diagnostics

Channel
Biopsies
Injections
Procedures
TEP

epiglottis adherent to post / lateral hypopharyngeal wall.

hyoid # - displaced posteriorly with epiglottis = inlet stenosis.
horizontal web of post hypo pharyngeal wall at level of superior aspect of epiglottis.
Approach; trans hyoid pharyngotomy.

Surgical
Primary resection and anastomosis
Laryngotracheoplasty (LTP)
Grafts (cartilage, mucosa)
Stenting
Single stage versus

multistage

skin incision( hyoid bone )
if hyoid # (

reduced& fixed, removed )
vallecula entered.
adhesion of epiglottis to post / lat wall
division along long axis.
sub mucosal excision of scar.
primary mucosal closure.
horizontal web
vertical incision – scar excised.
mucosal flaps undermined- horizontal line closure

mucosal defect – skin graft.
Full thickness loss –

radial forearm flap.
In case of post displacement of hyoid/ epiglttic cartilage,
laryngofissure
base of epiglottis identified.
ant fascia, perichondrium ,& epiglottis incised inverted V shape.
Mucoperichondrium of epiglottis elevated superiorly.
Scar tissue ,base of epiglottis excised
Mucoperichondrium incised & flaps turned outward and sewn to ant epiglottis
Thyrotomy closed.

thyroid cartilage #/ mucosal disruption
two opposing raw

surfaces heals by fibrosis
thin/ thick web – hoarseness/ airway compromise.
successful repair requires physical seperation of opposing edge until epithelialization is complete.

CO2 laser excision – keel insertion
keel inserted –

endoscopically /mini cricho thyrotomy
Ideal keel ;
stable, inert
extension- cricho thyriod membrane to 2-3 mm above ant commissure.
post wing at vocal process not in post commissure.
if extends above petiole, angle should be 120^.

indications;
sub glottic extension >5 mm
inlet stenosis.

failed endoscopy.
scar excised preserving mucosa
mucoal defect- labial mucosal/ skin graft with short term stenting with montgomery tube/ Mc Naught tantalum keel.

intubation (most common)

_ cricho arytenoid joint arthritis.
repair
endoscopic excision of web.
Co2 laser.
laryngofissure- submucosal excision of scar
endoscopic laser arytenoidectomy (type 4 )
Post crichoid split with rib cartilage grafting.

stay of treatment )
Stenosis divided at midline.
scar excised

preserving mucosa & developing mucosal flap from AEF.
If extensive area is devoid of mucosa- grafting (buccal mucosa, septal mucosa, SSG, ) is done.
Graft sutured in place and stent kept.
Stent removed at a later date.

stenosis with 50% reduction in A-P diameter of glottis.

midline thyrotomy
submucosal scar excision
base of epiglottis identified.
epiglottis pulled inferiorly to crichoid arch and sutured to thyroid (lat ) , crichoid (inferiorly ).

laser excision and repair with micro trap door flap

– circumferrential sub glottic stenosis.
Radial incision at 12, 3, 6, 9 O’ clock position – bronchoscopic dilatation.

hyoid sterno hyoid muscle interposition graft .
thyroid sterno

thyroid pedicle graft.
costal cartilage / septal cartilage grafting
post crichoid lamina split & internal rigid stenting.
partial cricoid resection with thyro tracheal anastomosis.
risk RLN injury.
need for laryngeal release.
neck kept in complete flextion in post – op.

a higher level
funnel shape; midcricoid area 2-3 mm

below cords narrowest.
small and narrow lumen.
mucosa has loose areolar tissue with abundant sub mucosal fluid.

sub glottic stenosis
vocal cord paralysis
sub glottic hemangioma

laryngomalacia/ tracheomalacia.
acquired
inflammatory
neoplastic
traumatic

techniques
ant cricoid split
laryngo tracheoplasty
laryngo tracheal reconstruction

crico tracheal resection and anastomosis

antibiotic cover
anti reflux medication 6 wk
endoscopy- granulation

removal
stent removal 6-8 wks
anastomotic complications;
granulations
stenosis
dehiscence

fetal fibroblasts transposition( IL6,8)
tissue engineered scaffolds (hyaluronic acid/

caboxy methyl cellulose )
marlex mesh tube covered with collagen sponge.