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Презентация на тему Trypanosomiasis

Содержание

2. Historyits species was discovered by a scientist
3. IntroductionThe name is derived from Greek word,
4. Trypanosoma
5. Morphology of trypanosome
6. African Trypanosomiasis (Sleeping Sickness)
7. The parasites Belong to a group of
8. T. rhodesiense causes E. African trypanosomiasisT. gambiense causes W. and Central African sleeping sicknessDistribution
9. Trypanosoma brucei species
11. TransmissionA bite from an infected tsetse fly
12. Life cycle
13. Pathogenesis
14. Clinical presentationIncubation period may be from few
16. Clinical presentation
17. Diagnosis
18. DiagnosisGeneralAnemia, hypergammaglobulinemia, low complement levels, elevated ESR,
19. Imaging StudiesCT scanning and MRI of the
20. Treatment
21. American Trypanosomiasis ( Chagas Disease)
22. Distribution
23. Morphology
24. Transmission
25. Life cycle
26. Transmission
27. Pathogenesis
28. Pathogenesis
29. Diagnosis
30. Diagnosis (Xenodiagnosis)
31. Diagnosis
32. Chronic stage. In chronic stage these parasites
33. Gigantism of midgutClinical presentation
34. Treatment
35. Скачать презентацию
36. Похожие презентации

Historyits species was discovered by a scientist Valentine” in 1841. But these are found in mammals after 50 – 80 years later. Then further studied about their diseases.

TrypanosomiasisThe topic of the lecture:Professor Kutmanova A.Z.

IntroductionThe name is derived from Greek word, trypano means (borer) soma means

African Trypanosomiasis (Sleeping Sickness)

The parasites Belong to a group of closely related trypanosomes in the

T. rhodesiense causes E. African trypanosomiasisT. gambiense causes W. and Central African sleeping sicknessDistribution

TransmissionA bite from an infected tsetse fly causes African trypanosomiasis.Blood transfusions are

Clinical presentationIncubation period may be from few days to weeks. The first

DiagnosisGeneralAnemia, hypergammaglobulinemia, low complement levels, elevated ESR, thrombocytopenia, hypoalbuminemia, but not eosinophilia

Imaging StudiesCT scanning and MRI of the head: Both head CT scanning

American Trypanosomiasis ( Chagas Disease)

Chronic stage. In chronic stage these parasites reside in heart and midgut,

Gigantism of midgutClinical presentation

Слайды презентации

Слайд 2 History
its species was discovered by a scientist Valentine”

Historyits species was discovered by a scientist Valentine” in 1841. But

in 1841.
But these are found in mammals after

50 – 80 years later.
Then further studied about their diseases.

Слайд 3 Introduction
The name is derived from Greek word,
trypano

IntroductionThe name is derived from Greek word, trypano means (borer) soma

means (borer)
soma means (body)
They are unicellular flagellate

protozoa.
Have spiral like motion.
Need more than one host to complete its life cycle.
Oftenly transmitted by a vector.
Generally found in intestine, but some time found in blood stream or in heart.

Слайд 4 Trypanosoma

Слайд 5 Morphology of trypanosome

Слайд 6 African Trypanosomiasis (Sleeping Sickness)

Слайд 7 The parasites
Belong to a group of closely

The parasites Belong to a group of closely related trypanosomes in

related trypanosomes in the Trypanosoma brucei species complex. Three

morphologically indistinguishable species are recognized:
T. brucei infects game animals/livestock (causes nagana)
T. rhodesiense causes E. African trypanosomiasis
T. gambiense causes W. and Central African sleeping sickness
(Some authors consider these as subspecies: T. brucei brucei, T. b. rhodesiense, T. b. gambiense.)

Слайд 8 T. rhodesiense causes E. African trypanosomiasis
T. gambiense causes W. and

Central African sleeping sickness
Distribution

Слайд 9 Trypanosoma brucei species

Слайд 10

Слайд 11 Transmission
A bite from an infected tsetse fly causes

TransmissionA bite from an infected tsetse fly causes African trypanosomiasis.Blood transfusions

African trypanosomiasis.
Blood transfusions are a rare cause of parasitic

transmission.
In rare cases, accidental transmission in the laboratory has been implicated.

Слайд 12 Life cycle

Слайд 13 Pathogenesis

Слайд 14 Clinical presentation
Incubation period may be from few days

Clinical presentationIncubation period may be from few days to weeks. The

to weeks.
The first clinical manifestation of African trypanosomiasis

chancre occurs at the site of inoculation .

Слайд 15

Слайд 16 Clinical presentation

Слайд 17 Diagnosis

Слайд 18 Diagnosis
General
Anemia, hypergammaglobulinemia, low complement levels, elevated ESR, thrombocytopenia,

DiagnosisGeneralAnemia, hypergammaglobulinemia, low complement levels, elevated ESR, thrombocytopenia, hypoalbuminemia, but not

hypoalbuminemia, but not eosinophilia or abnormal liver function.
The

total IgM level is higher in blood and CSF.
A definitive diagnosis of infection requires actual detection of trypanosomes in blood, lymph nodes, CSF, skin chancre aspirates, or bone marrow.
However, symptomatic improvement after empiric treatment is the usual confirmatory test in areas where diagnostic studies are not readily available.

Слайд 19 Imaging Studies
CT scanning and MRI of the head:

Imaging StudiesCT scanning and MRI of the head: Both head CT

Both head CT scanning and MRI reveal cerebral edema

and white matter enhancement, respectively, in patients with late-stage African trypanosomiasis.
EEG in neurologic involvement usually shows slow wave oscillations (delta waves), a nonspecific finding