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Презентация на тему Rheumatic endocardites

PlanEndocarditisInfective endocarditisNon-infective endocarditisNonbacterial thrombotic endocarditisLibman-Sacks endocarditisDiagnosticsReferences
Rheumatic   endocarditesStudent:Nurmakhan ArnatGroup:002-01 PlanEndocarditisInfective endocarditisNon-infective endocarditisNonbacterial thrombotic endocarditisLibman-Sacks endocarditisDiagnosticsReferences Endocarditis is an inflammation of the inner layer of There are multiple ways to classify endocarditis. The simplest classification Infective endocarditis  Since the valves of the heart do not receive Non-infective endocarditis Nonbacterial thrombotic endocarditisLibman-Sacks endocarditis Nonbacterial thrombotic endocarditis  Nonbacterial thrombotic endocarditis (NBTE), also called marantic endocarditis Another form of sterile endocarditis, is termed Libman-Sacks endocarditis; this DIAGNOSTICS  Examination of suspected infective endocarditis includes a detailed examination of Thank you for your attention!!! ReferencesCopyright © 2004 - 2014 Atlas of Pathologywww.wikipedia.enemedicine.medscape.com
Слайды презентации

Слайд 2 Plan
Endocarditis
Infective endocarditis
Non-infective endocarditis
Nonbacterial thrombotic endocarditis
Libman-Sacks endocarditis
Diagnostics
References

PlanEndocarditisInfective endocarditisNon-infective endocarditisNonbacterial thrombotic endocarditisLibman-Sacks endocarditisDiagnosticsReferences

Слайд 3 Endocarditis is an inflammation of

Endocarditis is an inflammation of the inner layer of

the inner layer of the heart, the endocardium. It

usually involves the heart valves (native or prosthetic valves). Other structures that may be involved include the interventricular septum, the chordae tendineae, the mural endocardium, or even the surfaces of intracardiac devices. Endocarditis is characterized by a prototypic lesion, the vegetation, which is a mass of platelets, fibrin, microcolonies of microorganisms, and scant inflammatory cells

Слайд 4 There are multiple ways to classify

There are multiple ways to classify endocarditis. The simplest classification

endocarditis. The simplest classification is based on etiology: either

infective or non-infective, depending on whether a microorganism is the source of the inflammation or not. Regardless, the diagnosis of endocarditis is based on clinical features, investigations such as an echocardiogram, and blood cultures demonstrating the presence of endocarditis-causing microorganisms.


Слайд 5 Infective endocarditis
Since the valves of the

Infective endocarditis Since the valves of the heart do not receive

heart do not receive any dedicated blood supply, defensive

immune mechanisms (such as white blood cells) cannot directly reach the valves via the bloodstream. If an organism (such as bacteria) attaches to a valve surface and forms a vegetation, the host immune response is blunted. The lack of blood supply to the valves also has implications on treatment, since drugs also have difficulty reaching the infected valve.
Normally, blood flows smoothly past these valves. If they have been damaged (from rheumatic fever, for example) the risk of bacteria attachment is increased

Слайд 7 Non-infective endocarditis
Nonbacterial thrombotic endocarditis
Libman-Sacks endocarditis

Non-infective endocarditis Nonbacterial thrombotic endocarditisLibman-Sacks endocarditis

Слайд 8 Nonbacterial thrombotic endocarditis
Nonbacterial thrombotic endocarditis (NBTE),

Nonbacterial thrombotic endocarditis Nonbacterial thrombotic endocarditis (NBTE), also called marantic endocarditis

also called marantic endocarditis is most commonly found on

previously undamaged valves. As opposed to infective endocarditis, the vegetations in NBTE are small, sterile, and tend to aggregate along the edges of the valve or the cusps. Also unlike infective endocarditis, NBTE does not cause an inflammation response from the body. NBTE usually occurs during a hypercoagulable state such as system wide bacterial infection, or pregnancy, though it is also sometimes seen in patients with venous catheters. NBTE may also occur in patients with cancers, particularly mucinous adenocarcinoma

Слайд 10 Another form of sterile endocarditis, is

Another form of sterile endocarditis, is termed Libman-Sacks endocarditis; this

termed Libman-Sacks endocarditis; this form occurs more often in

patients with lupus erythematosus and is thought to be due to the deposition of immune complexes. Also unlike NBTE, Libman-Sacks endocarditis does not seem to have a preferred location of deposition and may form on the undersurfaces of the valves or even on the endocardium.

Libman-Sacks endocarditis


Слайд 12 DIAGNOSTICS
Examination of suspected infective endocarditis includes

DIAGNOSTICS Examination of suspected infective endocarditis includes a detailed examination of

a detailed examination of the patient, and especially careful

cardiac auscultation, various blood tests, ECG, cardiac ultrasound (echocardiography). The decisive role played by echocardiography in the diagnosis (through the anterior chest wall or transesophageal), with which you can reliably establish the presence of microbial vegetation, the degree of valvular and violations of the pumping function of the heart.


Слайд 14 Thank you for your attention!!!

Thank you for your attention!!!

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